neuroprotective properties — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8849	PF-9601N		MAO
	PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.		MAO
T1308	Orphenadrine hydrochloride	Mebedrol,Mephenamin	Sodium Channel , NMDAR , Norepinephrine , iGluR , Histamine Receptor
	Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
T6618	Orphenadrine Citrate	Flexon,Flexoject,Banflex	AChR , iGluR
	Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.		AChR , iGluR
T2343	AS601245		JNK
	AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.		JNK
T21470L	Davunetide acetate	Davunetide acetate(211439-12-2 Free base)	Beta Amyloid , Microtubule Associated
	Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing peptide and inhibits Aβ aggregation and Aβ-induced neurotoxicit...		Beta Amyloid , Microtubule Associated
T65135	Kynurenic acid	Fibrostop 2,Quinurenic acid	GPR , GluR , NMDAR
	Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and an agonist of GPR35/CXCR8 with neuroprotective and anticonv...		GPR , GluR , NMDAR
Fr12596	3-Acetylcoumarin		Others
	3-Acetylcoumarin as a practical ligand for copper-catalyzed CN coupling reactions at room temperature. It has neuroprotective and acaricidal properties.		Others
T21268L	Semax acetate(80714-61-0 free base)		Others
	Semax acetate is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties.		Others
T5S2076	Senkyunolide I		Others , Caspase
	1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.		Others , Caspase
T2737	Neohesperidin	Hesperetin 7-O-neohesperidoside,NSC 31048	Antioxidant
	Neohesperidin (NSC-31048) with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model.		Antioxidant
T6S1101	Astragalin	Kaempferol 3-D-glucoside,Kaempferol 3-O-glucoside,kaempferol-3-glucoside,3-Glucosylkaempferol,Astragaline,Kaempferol 3-β-D-glucopyranoside	Apoptosis , NF-κB
	Astragalin (Kaempferol 3-O-glucoside) is a biologically active natural flavonoid. It has a variety of pharmacological properties, including antioxidant, anti-inflammatory, anti-cancer, neuroprotective, and cardioprotecti...		Apoptosis , NF-κB
T2827	Asiatic acid	Asiantic acid,Dammarolic acid	Apoptosis , p38 MAPK , Parasite
	Asiatic acid (Dammarolic acid) is the aglycone of asiaticoside used in wound healing with antioxidant, anti-inflammatory, and neuroprotective properties.		Apoptosis , p38 MAPK , Parasite
T67908	ThioLox		Lipoxygenase
	ThioLox is a competitive 15-lipoxygenase-1 (15-LOX-1) inhibitor with IC50 value of 12 μM. ThioLox shows anti-inflammatory and neuroprotective properties. It has anti-inflammatory and neuroprotective effects, and has a st...		Lipoxygenase
T2883	Syringic acid	3,5-dimethyl ether Gallic Acid,SYRA,3,5-dimethoxy-4-hydroxy Benzoic Acid,NSC 2129	Others , Endogenous Metabolite , Antibacterial
	Syringic acid (3,5-dimethoxy-4-hydroxy Benzoic Acid) (SYRA) is a potential antioxidant used in traditional Chinese medicine and is an emerging nutraceutical. It has potential anti-angiogenic, anti-glycating, anti-hypergl...		Others , Endogenous Metabolite , Antibacterial
T0437	Inosine	INO 495,NSC 20262	ROS , Endogenous Metabolite , Adenosine Receptor
	Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesic properties.		ROS , Endogenous Metabolite , Adenosine Receptor
TP1570L	Cortistatin-14 acetate	Cortistatin-14 acetate(186901-48-4 Free base)	Somatostatin
	Cortistatin-14 acetate, a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 acetate shows anticonvulsive, neuroprotective...		Somatostatin
TP1188L	Cortistatin 14, human, rat acetate		Somatostatin
	Cortistatin 14, human, rat acetate is a neuropeptide having structural similarity to somatostatin-14 and shows anticonvulsive, neuroprotective effects and remarkable anti-inflammatory properties. Cortistatin 14, human, r...		Somatostatin
TN1772	Isoastilbin		Anti-infection , Tyrosinase , Antibacterial
	Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, Isoastilbin has anti-acne an...		Anti-infection , Tyrosinase , Antibacterial
TN1420	Bacopaside I		Others
	Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 ...		Others
T22513	4-PPBP maleate		Sigma receptor , NMDAR
	4-PPBP maleate is a potent σ1 receptor (ligand) agonist. 4-PPBP maleate can be considered a selective, non-competitive NR1a/2B NMDA receptor antagonist in the context of Xenopus oocytes expression. 4-PPBP maleate has neu...		Sigma receptor , NMDAR